Split dosing of artemisinins does not improve antimalarial therapeutic efficacy
نویسندگان
چکیده
منابع مشابه
Maximizing antimalarial efficacy and the importance of dosing strategies
Artemisinin-based combination therapies (ACTs) are the cornerstone for the treatment of malaria. However, confirmed resistance to artemisinins in South-East Asia, and reports of reduced efficacy of ACTs raise major concerns for malaria treatment and control. Without new drugs to replace artemisinins, it is essential to define dosing strategies that maximize therapeutic efficacy, limit the sprea...
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متن کاملSplit dosing for bowel preparation.
DKR Thus far, I am aware of 12 trials that have directly compared split dosing with evening-before dosing for bowel preparation, and all but 1 of these trials found that split dosing was superior with regard to efficacy. None of the trials found evening-before dosing to be superior. In these studies, the benefits of split dosing were particularly evident in the ascending, or right, colon. The m...
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ژورنال
عنوان ژورنال: Scientific Reports
سال: 2017
ISSN: 2045-2322
DOI: 10.1038/s41598-017-12483-4